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G Umberto Meduri Selected Research

glucocorticoid receptor alpha

1/2005Nuclear factor-kappaB- and glucocorticoid receptor alpha- mediated mechanisms in the regulation of systemic and pulmonary inflammation during sepsis and acute respiratory distress syndrome. Evidence for inflammation-induced target tissue resistance to glucocorticoids.
6/2004Systemic inflammation-associated glucocorticoid resistance and outcome of ARDS.
4/2002Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome: evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids.

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G Umberto Meduri Research Topics

Disease

21Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
04/2020 - 02/2002
17Pneumonia (Pneumonitis)
01/2022 - 01/2005
15Inflammation (Inflammations)
01/2018 - 02/2002
8COVID-19
02/2021 - 04/2020
8Sepsis (Septicemia)
10/2016 - 01/2005
5Infections
01/2018 - 01/2008
5Septic Shock (Toxic Shock Syndrome)
04/2013 - 02/2005
4Critical Illness (Critically Ill)
01/2022 - 01/2008
4Respiratory Insufficiency (Respiratory Failure)
01/2021 - 09/2002
3Shock
01/2018 - 04/2007
3Acute Lung Injury
07/2011 - 01/2008
2Hyperglycemia
01/2018 - 06/2009
2Lung Injury
10/2016 - 02/2012
1Viral Pneumonia
02/2021
1Pathologic Processes
01/2021
1Organizing Pneumonia
01/2021
1Respiratory Sounds (Crackle)
03/2015
1Tachycardia (Tachyarrhythmias)
06/2013
1Aspiration Pneumonia
06/2011
1Fever (Fevers)
04/2010
1Superinfection
06/2009
1Hemorrhage
06/2009
1Hypernatremia
06/2009
1Adrenal Insufficiency (Adrenal Gland Hypofunction)
06/2008
1Pancreatitis
06/2008
1Liver Failure
06/2008
1Multiple Organ Failure (MODS)
04/2007
1Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
09/2002
1Acquired Immunodeficiency Syndrome (AIDS)
09/2002
1Glucocorticoid Receptor Deficiency
04/2002
1Cross Infection (Nosocomial Infection)
02/2002

Drug/Important Bio-Agent (IBA)

19GlucocorticoidsIBA
10/2020 - 04/2002
12Adrenal Cortex Hormones (Corticosteroids)IBA
02/2021 - 01/2008
11MethylprednisoloneFDA LinkGeneric
01/2022 - 04/2002
5Hydrocortisone (Cortisol)FDA LinkGeneric
10/2016 - 06/2004
3Oxygen (Dioxygen)IBA
10/2016 - 04/2010
3CytokinesIBA
12/2009 - 02/2002
3glucocorticoid receptor alphaIBA
01/2005 - 04/2002
3NF-kappa B (NF-kB)IBA
01/2005 - 04/2002
2Ascorbic Acid (Vitamin C)FDA LinkGeneric
02/2021 - 01/2021
2Thiamine (Aneurin)FDA Link
02/2021 - 01/2021
2Heparin (Liquaemin)FDA LinkGeneric
02/2021 - 01/2021
2Dexamethasone (Maxidex)FDA LinkGeneric
04/2012 - 06/2008
2Anti-Bacterial Agents (Antibiotics)IBA
06/2011 - 02/2005
2Proteins (Proteins, Gene)FDA Link
10/2010 - 07/2006
2C-Reactive ProteinIBA
04/2007 - 02/2005
1SilverIBA
01/2021
1SteroidsIBA
03/2015
1Glucose (Dextrose)FDA LinkGeneric
06/2013
1SodiumIBA
06/2013
1Protein CIBA
02/2012
1Interleukin-6 (Interleukin 6)IBA
02/2012
1proadrenomedullinIBA
02/2012
1Biomarkers (Surrogate Marker)IBA
02/2012
1AntibodiesIBA
10/2010
1AutoantigensIBA
10/2010
1AutoantibodiesIBA
10/2010
1LuciferasesIBA
10/2010
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
04/2010
1ChemokinesIBA
12/2009
1Vasoconstrictor AgentsIBA
06/2008
1Adrenocorticotropic Hormone (ACTH)FDA Link
06/2008
1Lactic Acid (Lactate)FDA LinkGeneric
04/2007
1EndotoxinsIBA
07/2006
1Pharmaceutical PreparationsIBA
01/2006
1Transcription Factors (Transcription Factor)IBA
06/2004

Therapy/Procedure

11Therapeutics
02/2021 - 04/2007
10Artificial Respiration (Mechanical Ventilation)
10/2020 - 09/2002
7Length of Stay
01/2018 - 04/2007
5Critical Care (Surgical Intensive Care)
02/2021 - 04/2007
2Secondary Prevention
04/2010 - 01/2008
1Mechanical Ventilators (Ventilator)
10/2020
1Patient Readmission
01/2018
1Aftercare (After-Treatment)
01/2018
1Duration of Therapy
09/2011
1Catheters
04/2007
1Noninvasive Ventilation
09/2002
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
09/2002